 Completed
Research |
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| Research
Activities Under Progress |
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| International
Clinical Studies |
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| Clinical
Studies Awaiting Approval |
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| Outreach
Services |
| RESEARCH & OUTREACH > COMPLETED RESEARCH | |
Completed Research |
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The
occurrence of late potential in Acute Myocardial Infarction and in
recovery and incidence of Ventricular Arhythmia - 1995 - 96. |
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The
incidence of silent Carotid Artery Disease-Doppler Imaging Assessment
in people with significant Coronary
Artery Disease - 1996 - 97. |
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Does
the surface ECG reflect the actual quantum of Coronary Artery Disease-Angiography
- ECG Correlation - 1997. |
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Nicorandil
Intravenous administration for Unstable Angina to compare its efficacy
with conventional Intravenous Nitroglycerine infusion in 50
patients during Acute Coronary Syndrome
with other conventional treatment. |
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Effects
of Fluvostatin on 50 patients who had combined Hyperlipidemia after
6 weeks of diet therapy. |
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The
influence of Ramipril on LV function in Post MI patients 1998-99. |
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The
influence of Beta Blockers on LV function in Post Infarct patients
1998-99. |
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First
dose Hypotension with Ace Inhibitors, Does it depend on the molecules
used - 1998. |
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The
maximum dose tolerability of Ramipril by Indian patients and its effect
on Renal Profile and Systemic Pressure - 2000. |
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Comparative
efficacy of Low Molecular Weight Heparin v/s Unfracturated Heparin
in Unstable Angine. |
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Coparative
assessment of luminal narrowing - cross section area of Coronary Arteries
by Angiography Vs Intravascular Ultrasound. |
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Application of
Myocardial contrast study in Unstable Angina and Acute Infarction
before and after intervention. |
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Creaton
of specific software for patient Data including history, Risk factors,
Lab data, Intervention Data etc. |
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The influence Hyperinsulinemia, Serum Fibrinogen Level, Autonomic Neuropathy,Plasminogen Activator Inhibitor, Homocystein in Diabetics, Tissue Plasminogen Activator with Cardio Vascular complication. |
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| RESEARCH & OUTREACH > RESEARCH ACTIVITIES UNDER PROGRESS | |
Research Activities Under Progress |
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Coronary
artery size in India – Male & Female , Age & Sex, body
surface area influence. |
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Normal
range of myocardial thickness in Indian adult population. |
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The
range of mitral and tricuspid value ring size, age and sex, BMI influence. |
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The
impact of exercise on blood pressure control on systemic hypertension
by beta-blockers and calcium blockers / ACE Inhibitor. |
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The
influence of exercise on moderate transvalvular gradient in rheumatic
& non-rheumatic and valvular stenotic lesion in the decision-making
for intervention. |
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The pattern of coronary artery disease in Diabetics Vs Non-Diabetics
based on angiographic profile. |
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The
influence of long term programmed exercise on low HDL level. |
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Action
of Nicotinic Acid beyond Cholesterol reduction in particular platelet
function. |
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The
influence of both topical and oral Nicotinic Acid on Lipid Profile. |
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Beyond
LDL Cholesterol – Is it necessary to modify NCEP guidelines
for CAD and its susceptibility, Grant by Ministry of Science and Technology,
Dept. of Science and Technology, Govt. of India. |
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| RESEARCH & OUTREACH > INTERNATIONAL CLINICAL STUDIES | |
International Clinical Studies |
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CREATE
STUDY – influence of low molecular weight herparin with Glucose
– Insulin - Potassium (GIK) Administration in
collaboration Mc Master University, Hamiltion Canada, Project
Director- Dr.Salim Yusuf – STILL ON |
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The
Hirulog Early Reperfusion Occlusion (HERO 2) Trial – An open
prospectively randomized comparison of Hirulog Versus Heparin
in patients receiving aspirin, thrombolysis (Streptokinase)
for the treatment of Acute Myocardial Infarction – COMPLETED,
PUBLISHED IN THE LANCET, DECEMBER 2001 |
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Enalarpril
in hypertension Crisis – Left Ventricular dysfunction –
STILL ON |
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Nicotinic
acid – the effects of nicotinic acid on plasma Triglycerides
and HDL cholesterol. |
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Create
Registry – Since there is no figure available now for
the actual incidence of unstable angina in indian patient.
This multicentre study initiated collaboration with St
Johns Medical College and Mcmaster Unversity , Canada – STILL
ON |
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A multi national and multi center douoble-blind, randomized, place-controlled Parallel group design study to evaluate the efficacy and safety of an extended infusion of Tedisamil Sesquifumurate in the rapid conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in subjects with recent onset Atrial Fibrillation or Flutter. |
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A
multi national and multi center douoble-blind, randomized, place-controlled
Parallel group design study to evaluate the efficacy and safety of
an extended infusion of Tedisamil Sesquifumurate in the rapid
conversion of Atrial Fibrillation or Flutter to Normal
Sinus Rhythm in subjects after Cardiac Surgery. |
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| RESEARCH & OUTREACH > CLINICAL STUDIES AWAITING APPROVAL | |
Clinical Studies Awaiting Approval |
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Phase
3 international multi-centric study in UnstableAngina / NSTEMI
evaluating the efficacy and safety of Fondaparinux, a synthetic
Oligosaccharide which is an indirect inhibitor
of Factor Xa- Oasis – 5. |
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Open-label,
randomized, multi-centre, phase III, parallel group study to compare
the efficacy and safety of Rosuvastatin and Atorvastain in Indian
subjects with type Iia and Iib Hypercholesterolaemia |
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Open
– label, multi-centre single arm study to Evaluate the efficacy
and safety of Metoprolol CR in patients with Hypertension (SIMPLE) |
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| RESEARCH & OUTREACH > OUTREACH SERVICES | |
Outreach Services |
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Regular
Cardiac screening Camps for the public are conducted in the institution, 
CGHS Camp - SRMC & RI, Chennai - 12.09.98.
WORLD HEART DAY - SRMC & RI, Chennai - 30.09.2001. |
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And
also at various locations outside the campus,
Kumuram Hospital, Vellore - 1995.
Bharani Hospital, Chennai - 1996.
Sri Sankara Health Center, Chennai - 06.04.1996.
Melrosapuram, Chengalpet - 19.07.1997.
Reserve Bank of India Staff College, Chennai - Stress & Management
for Executives.
Rotary club of Gudiyattam - 11.12.1997.
Innerwheel club of Madras Metro - Hazards of smoking - Loyola College,
Chennai - 24.02.1998.
Central Revenue Quarters - Anna Nagar, Chennai - 03.04.1999.
Padiyanallur village, Thiruvallur.
Andaman & Nicobar Islands - 11.04.1996.
Super Speciality Services Division at the Sacred Heart Hospital, Kumbakonam
- Monthly.
Sivasakthi Nagar Welfare Association, Chennai - 21.07.2001. |
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